Jardiance contains empagliflozin. It is used for blood-glucose control and for specific heart and kidney conditions. The reason for treatment determines which eligibility criteria and dosing instructions apply.
The approved uses and formulations described here follow US prescribing information. They may differ in other countries.
| Medicine detail | Details |
|---|---|
| Active ingredient(s) | empagliflozin |
| Medicine class | SGLT2 inhibitor |
| Forms and strengths | Oral tablets: 10 and 25 mg |
Approved uses in the United States
The label includes glucose control in type 2 diabetes from age 10. Adult indications also include heart failure, chronic kidney disease at risk of progression, and reduction of cardiovascular death in type 2 diabetes with established cardiovascular disease. Each indication has defined criteria and limitations. For side-by-side product context, use the Jardiance Vs Farxiga Comparator. For coverage and payment questions, read the Jardiance Vs Farxiga US cost comparison.
Source: [1]
Tablets and kidney effects
Empagliflozin blocks SGLT2 in the kidneys, increasing the amount of glucose passed in urine. Jardiance tablets contain 10 or 25 mg. A higher dose may be prescribed for glucose control, but it does not mean greater heart or kidney protection. Kidney function and the reason for treatment guide the regimen.
Source: [1]
Recognizing ketoacidosis risk
Ketoacidosis can occur without markedly elevated blood glucose. Illness, reduced food intake, fasting and surgery can change risk. Ask for a clinician-directed plan for these situations. Severe symptoms need assessment even if a glucose reading does not look unusually high.
Source: [1]
Hydration and infection precautions
Volume depletion, genital fungal infection, serious urinary infection and rare severe perineal infection are relevant warnings. Review kidney function, diuretics and symptoms of dehydration with the clinical team. Foot health also deserves attention under the current label’s precautions.
Source: [1]
Jardiance and combination tablets
Synjardy combines empagliflozin with metformin; Glyxambi combines it with linagliptin. Their additional ingredients bring different precautions, and their approved uses differ from Jardiance’s. Check the full product name when discussing a prescription.
Source: [1]
Questions and answers
Is Jardiance only used in people with diabetes?
No. Some adults receive Jardiance for heart failure or chronic kidney disease without having diabetes. The prescriber checks the criteria and limitations for the intended use.
Does 25 mg mean more heart protection than 10 mg?
That conclusion should not be drawn from tablet strength. The indication-specific label and prescriber determine the regimen.
Is Synjardy simply another Jardiance brand?
No. It adds metformin and has a separate combination label.
Related reading
Sources
Sources checked 1 October 2026. This information does not replace advice from your healthcare professional. For complete warnings and instructions, read the product information and consult the prescribing team.
Reviewed by: Mattias Hagman, PhD
About the reviewer:
Dr Mattias Hagman (PhD, University of Sydney) has an academic background and experience working with healthcare-related content and regulated industries. He has lecturing experience at international universities, including Stockholm University and the University of Malta.
Last reviewed: October 2026