Farxiga contains dapagliflozin. Its US uses extend beyond glucose lowering, so the reason it was prescribed matters when interpreting kidney-function limits and expected treatment goals.
The approved uses and formulations described here follow US prescribing information. They may differ in other countries.
| Medicine detail | Details |
|---|---|
| Active ingredient(s) | dapagliflozin |
| Medicine class | SGLT2 inhibitor |
| Forms and strengths | Oral tablets: 5 and 10 mg |
Approved uses in the United States
Farxiga is approved to improve glucose control in people aged 10 years and older with type 2 diabetes. It also has specific uses in adults with heart failure or chronic kidney disease, and for reducing heart-failure hospitalization in adults with type 2 diabetes and established cardiovascular disease or multiple risk factors. The criteria differ for each use. For side-by-side product context, use the Jardiance Vs Farxiga Comparator. For coverage and payment questions, read the Jardiance Vs Farxiga US cost comparison.
Source: [1]
How dapagliflozin works
Dapagliflozin blocks the kidney’s SGLT2 transporter, increasing the amount of glucose passed in urine. Farxiga tablets contain 5 or 10 mg. The kidney-function requirements depend on why it is prescribed: its effect on blood glucose and its use for heart or kidney disease are assessed differently.
Source: [1]
Ketoacidosis can be missed
The label warns about ketoacidosis, which can occur even when blood glucose is not markedly elevated. Illness, fasting and procedures may require a clinician-directed interruption plan. Ask for that plan in advance rather than judging safety only from a home glucose reading.
Source: [1]
Other precautions
Volume depletion, genital fungal infections, serious urinary infections and rare serious infection around the genital/perineal area are labeled concerns. Kidney function, hydration and interacting treatment such as diuretics need review. Symptoms suggesting serious infection or ketoacidosis require urgent assessment.
Source: [1]
Farxiga and Xigduo XR
Farxiga contains dapagliflozin alone. Xigduo XR combines it with metformin, which adds its own safety restrictions. The two products have different approved uses and are not automatically suitable for the same people.
Source: [1]
Questions and answers
Is Farxiga only a diabetes medicine?
No. The US label also includes defined adult heart-failure and chronic-kidney-disease uses.
Is Farxiga the same as Xigduo XR?
No. Xigduo XR adds metformin and has a separate label.
Can a normal-looking glucose reading rule out ketoacidosis?
No. SGLT2-associated ketoacidosis can occur without markedly elevated glucose; concerning symptoms need medical assessment.
Related reading
Sources
Sources checked 1 October 2026. This information does not replace advice from your healthcare professional. For complete warnings and instructions, read the product information and consult the prescribing team.
Reviewed by: Mattias Hagman, PhD
About the reviewer:
Dr Mattias Hagman (PhD, University of Sydney) has an academic background and experience working with healthcare-related content and regulated industries. He has lecturing experience at international universities, including Stockholm University and the University of Malta.
Last reviewed: October 2026